Chlorthalidone is approved by the Food and Drug Administration (FDA) to treat high blood pressure and edema. Edema is retained fluid or swelling.

Some doctors also prescribe chlorthalidone for:

  • Kidney stones
  • Meniere’s disease (dizziness and ringing in the ears)
  • Hypoparathyroidism (underactive parathyroid glands that can cause low blood calcium)
  • Diabetes insipidus (a hormone problem that leads to too much urination)