Spironolactone is approved by the Food and Drug Administration (FDA) to treat:
- High blood pressure
- Doctors often recommend spironolactone when a person’s blood pressure is still high even after taking several high blood pressure medicines
- Severe heart failure
- A hormone disorder that leads to high blood pressure called primary hyperaldosteronism
- Swelling from fluid buildup (called edema), caused by kidney disorders, heart failure, or liver disease
- Low blood potassium (hypokalemia)
Doctors may also prescribe spironolactone to treat acne or excessive hair growth on the face, chest, or back.