Angiotensin-converting enzyme (ACE) inhibitors are usually taken by mouth as a pill once or twice a day. There are 10 types of ACE inhibitors available in the United States to treat high blood pressure. Each has different tablet doses available.

Most people begin with the suggested starting dose, taking the pill once a day. Your doctor will work with you to adjust the dose to meet your blood pressure goals. Sometimes this means raising the dose, lowering the dose, or adding a second dose later in the day.

Most ACE inhibitors can be taken with or without food. Three ACE inhibitors—captopril, perindopril, and moexipril—should be taken on an empty stomach to get the best effect from the medicine. This means taking it at least one hour before or two hours after eating.

Always take your ACE inhibitor pills at the same time every day. Morning, evening, or mid-day—you decide what works best for you.

Take your ACE inhibitor the same time every day, that’s the way!