There are several medicines you should avoid if you are taking an angiotensin-converting enzyme (ACE) inhibitor:

  • Sacubitril/valsartan (brand name Entresto)
  • Aliskiren (brand name Tektuma), especially if you have diabetes

There are also medicines that may give you more side effects if you take them with ACE inhibitors, or they might make your ACE inhibitor not work as well. These include:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like Advil, Aleve, Motrin, and Midol
  • Potassium supplements
  • Some herbal supplements including ginseng, bitter orange, ginkgo, goldenseal, mate, Irish moss, kelp, and licorice

Your doctor may want to monitor you closely depending on what medicines or supplements you’re taking. Always discuss the medicines you’re currently taking with your doctor, both prescribed and over the counter.

Don’t take together or you’ll be under the weather!