You don’t need to avoid any activities when taking spironolactone. But be careful with activities that might be dangerous if you get dizzy, such as climbing a ladder or driving a car. If you are dizzy, it may mean your blood pressure is too low. It may also mean you are dehydrated. Exercise or being in a hot place might bring this on. Let your doctor know if this happens. They may ask you to take it easy until your body gets used to the medicine. Sometimes they need to change the dose of spironolactone. You can usually start your usual activities again once you know how you react to the new medicine.